Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart; placenta; pancreas; lung and liver; it is weakly expressed in the spleen; lymph nodes; and thymus. PDCD1LG2 is involved in the costimulatory signal; essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Recombinant Human PD-L2/CD273 Protein (mFc Tag)
£93.60 – £297.00 excluding VAT
Size | 10µg, 50µg |
---|---|
Active Protein | |
Activity | |
Protein Construction | Recombinant Human PD-L2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a mFc tag at the C-terminus. |
Sequence | Leu20-Pro219 |
Fusion Tag | C-mFc |
Accession | Q9BQ51 |
Species | Human |
Expressed Host | Human Cells |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Mol Mass | 49.2 kDa |
AP Mol Mass | 60-90 kDa |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Research Areas | immunology |
Reconstitution | Please refer to the printed manual for detailed information. |
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