Fagus Antibody Services

Recombinant Human PDCD4 protein (His Tag)

£79.20£239.20 excluding VAT

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation.

Size

20µg, 100µg

Active Protein

Active protein

Activity

Immunogen(E-AB-40340)

Protein Construction

A DNA sequence encoding the Human PDCD4(Q53EL6) (1M-325N) was expressed with a polyhistidine tag at the N-terminus.

Sequence

1M-325N

Fusion Tag

N/C-His

Accession

Q53EL6

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin

Please contact us for more information.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

36.9kDa

AP Mol Mass

41-43kDa

Formulation

Lyophilized from sterile PBS, pH 7.4

Research Areas

Cell biology, Cancer, epigenetics and nuclear signal

Reconstitution

Please refer to the printed manual for detailed information.

Related Product