Fagus Antibody Services

Recombinant Human platelet membrane glycoprotein IV/CD36/SR-B3 Fc Chimera Protein(Fc Tag)

£88.80£297.00 excluding VAT

Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1,oxidized lowdensity lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, β amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparuminfected erythrocytes. CD36 is required for the antiangiogenic effects of thrombospondin-1 in the corneal neovascularization assay. It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human platelet membrane glycoprotein IV is produced by our Mammalian expression system and the target gene encoding Gly30-Asn439 is expressed with a Fc tag at the C-terminus.

Sequence

Gly30-Asn439

Fusion Tag

C-Fc

Accession

P16671

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 90% as determined by reducing SDS-PAGE

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

73.8 kDa

AP Mol Mass

90-130 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Research Areas

Microbiology, Cardiovascular, Cancer, immunology, metabolism, Stem cells

Reconstitution

Please refer to the printed manual for detailed information.

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