Fagus Antibody Services

Recombinant Human PPIase/PPIL1 Protein (aa 1-166, His Tag)

£178.40£593.00 excluding VAT

Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ;skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 is produced by our E.coli expression system and the target gene encoding Met1-Gly166 is expressed with a 6His tag at the N-terminus.

Sequence

Met 1-Gly166

Fusion Tag

N-6His

Accession

Q9Y3C6

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass

20.4 kDa

AP Mol Mass

19 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH 8.0.

Research Areas

Signal Transduction, epigenetics and nuclear signal, immunology

Reconstitution

Not Applicable

Related Product