Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ;skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.
Recombinant Human PPIase/PPIL1 Protein (aa 1-166, His Tag)
£178.40 – £593.00 excluding VAT
SKU
FAS-033304-P
Category Protein
Tag Peptidyl-Prolyl Cis-Trans Isomerase-Like 1; PPIase; Rotamase PPIL1; PPIL1; CYPL1
Size | 10µg, 50µg |
---|---|
Active Protein | |
Activity | |
Protein Construction | Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 is produced by our E.coli expression system and the target gene encoding Met1-Gly166 is expressed with a 6His tag at the N-terminus. |
Sequence | Met 1-Gly166 |
Fusion Tag | N-6His |
Accession | Q9Y3C6 |
Species | Human |
Expressed Host | E.coli |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
Purity | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per µg as determined by the LAL method. |
Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Mol Mass | 20.4 kDa |
AP Mol Mass | 19 kDa |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH 8.0. |
Research Areas | Signal Transduction, epigenetics and nuclear signal, immunology |
Reconstitution | Not Applicable |
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