Fagus Antibody Services

Recombinant Human PSG6/PSG10 Protein (His Tag)

£684.00£855.00 excluding VAT

PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.

Size

100µg

Active Protein
Activity
Protein Construction

A DNA sequence encoding the human PSG6 (Met 1-His 424) (NP_001027020) was expressed, with a C-terminal polyhistidine tag.

Sequence

Met 1-His 424

Fusion Tag

C-His

Accession

NP_001027020

Species

Human

Expressed Host

Baculovirus-Insect Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 87 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

45.2 kDa

AP Mol Mass

58 kDa

Formulation

Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4

Research Areas

Tags & Cell Markers

Reconstitution

Please refer to the printed manual for detailed information.

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