PTH2, also known as PTRH2, is a mitochondrial protein which belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.
Recombinant Human PTH2/PTRH2 Protein (His Tag)
£684.00 – £855.00 excluding VAT
| Size | 100µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | A DNA sequence encoding the human PTRH2 (Q9Y3E5) (Gly63-Tyr179) was expressed with a polyhistidine tag at the N-terminus. |
| Sequence | Gly63-Tyr179 |
| Fusion Tag | N-His |
| Accession | Q9Y3E5 |
| Species | Human |
| Expressed Host | E.coli |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 14.5 kDa |
| AP Mol Mass | 14 kDa |
| Formulation | Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.0 |
| Research Areas | Cell biology, Cancer, epigenetics and nuclear signal, metabolism |
| Reconstitution | Please refer to the printed manual for detailed information. |
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