Fagus Antibody Services

Recombinant Human Resistin Protein (His Tag)

£93.60£339.00 excluding VAT

SKU FAS-033313-P Category

Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause “high levels of ‘bad’ cholesterol (low-density lipoprotein or LDL); increasing the risk of heart disease; resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human Adipose tissue-specific secretory factor is produced by our E.coli expression system and the target gene encoding Lys19-Pro108 is expressed with a 6His tag at the C-terminus.

Sequence

Lys19-Pro108

Fusion Tag

C-6His

Accession

NP_065148.1

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

10.6 kDa

AP Mol Mass

10-14 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM Acetic acid, pH 3.0.

Research Areas

Signal Transduction, Cardiovascular, metabolism

Reconstitution

Please refer to the printed manual for detailed information.

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