Fagus Antibody Services

Recombinant Human RGMA Protein (E.coli, His Tag)

£210.40£447.00 excluding VAT

Repulsive guidance molecule A(RGMA) is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1; BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human Repulsive guidance molecule A is produced by our E.coli expression system and the target gene encoding Pro169-Gly422 is expressed with a 6His tag at the N-terminus.

Sequence

Pro169-Gly422

Fusion Tag

N-6His

Accession

NP_064596.2

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass

29.8 kDa

AP Mol Mass

30 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.

Research Areas

Neuroscience, Stem cells

Reconstitution

Not Applicable

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