Fagus Antibody Services

Recombinant Human S100A16/S100F Protein

£68.80£250.00 excluding VAT

S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-handmotifs. S100 proteins are cell-and tissue-specific and are involved in many intra-and extracellular processes hrough interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has been obtained both in the solid state and insolution; resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S100A16 was also calculated in the calcium(II)-bound form. Immunoprecipitation analysis revealed that S100A16 could physically interact with tumor suppress or protein p53; also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S100A16 led to the inhibition or activation of the expression of p53-responsivegenes; respectively. S100A16 protein is a novel adipogenesis-promoting factor.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human S100A16 is produced by our E.coli expression system and the target gene encoding Met1-Ser103 is expressed.

Sequence

Met1-Ser103

Fusion Tag
Accession

Q96FQ6

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

11.8 kDa

AP Mol Mass

22 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 500mM NaCl, pH8.0.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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