S100A4 is a member of the S100 family of proteins. The S100 family is further classified as a member of the EF-hand superfamily of Ca++-binding proteins. These participate in both calcium-dependent and calcium-independent protein-protein interactions. The hallmark of this superfamily is the EF-hand motif that consists of a Ca++-binding site flanked by two α-helices (helix E and helix F) that were originally identified in a right-handed model of carp muscle calcium-binding protein. Human S100A4 is 101 amino acids (aa) in length. It contains two EF hand domains, one between aa 12-47, and a second between aa 50-85. S100A4 activity has been associated with cell transformation. It seems likely this is either coincidental, or a consequence, rather than a cause of transformation.
Recombinant Human S100A4 Protein (His Tag)
£73.60 – £268.00 excluding VAT
Size | 10µg, 50µg |
---|---|
Active Protein | |
Activity | |
Protein Construction | Recombinant Human S100A4 is produced by our E.coli expression system and the target gene encoding Met1-Lys101 is expressed with a 6His tag at the C-terminus. |
Sequence | Met1-Lys101 |
Fusion Tag | C-His |
Accession | P26447 |
Species | Human |
Expressed Host | E.coli |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Mol Mass | 12.6 kDa |
AP Mol Mass | 13 kDa |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Research Areas | Signal Transduction, Cardiovascular, Cancer |
Reconstitution | Please refer to the printed manual for detailed information. |
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