SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes.
Recombinant Human SERPINB1/PI2 Protein (Baculovirus, His Tag)
£585.60 – £732.00 excluding VAT
| Size | 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | A DNA sequence encoding the human SERPINB1 (P30740) (Met 1-Pro 379) was fused with a polyhistidine tag at the C-terminus. |
| Sequence | Met 1-Pro 379 |
| Fusion Tag | C-His |
| Accession | P30740 |
| Species | Human |
| Expressed Host | Baculovirus-Insect Cells |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per µg of the protein as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 44 kDa |
| AP Mol Mass | 44 kDa |
| Formulation | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% gly |
| Research Areas | Cell biology, Cardiovascular |
| Reconstitution | Please refer to the printed manual for detailed information. |
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