Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils); and found in liver; fetal liver; bone marrow; placenta; spleen and in lower levels in skeletal muscle; fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2;3- or alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Recombinant Human SIGLEC9/CD329 Protein (His Tag)(Active)
£142.40 – £523.00 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | Active protein |
| Activity | Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Approximately 93% will adhere after 5-10 mins incubation at 37 °C. |
| Protein Construction | Recombinant Human SIGLEC9 is produced by our Mammalian expression system and the target gene encoding Gln18-Gly348(Lys100Glu;Ala315Glu) is expressed with a 6His tag at the C-terminus. |
| Sequence | Gln18-Gly348(Lys100Glu;Ala315Glu) |
| Fusion Tag | C-His |
| Accession | Q9Y336 |
| Species | Human |
| Expressed Host | Human Cells |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 36.9 kDa |
| AP Mol Mass | 55-90 kDa |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS，2mMEDTA，ph7.4. |
| Research Areas | Tags & Cell Markers, Cardiovascular, immunology |
| Reconstitution | Please refer to the printed manual for detailed information. |
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