Fagus Antibody Services

Recombinant Human STAT1 Protein

£103.20£375.00 excluding VAT

Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated; STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF); migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes; inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human Signal Transducer and Activator of Transcription 1 is produced by our E.coli expression system and the target gene encoding Met1-Val712 is expressed.

Sequence

Met 1-Val712

Fusion Tag
Accession

P42224-2

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

83.3 kDa

AP Mol Mass

85 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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