Fagus Antibody Services

Recombinant Human Syndecan-1/SDC1 Protein (Fc Tag)

£103.20£375.00 excluding VAT

SKU FAS-033514-P Category Tag

Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding; cell signaling; and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence; and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation; cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human Syndecan-1 is produced by our Mammalian expression system and the target gene encoding Gln18-Glu251(Leu136Gln) is expressed with a Fc tag at the C-terminus.

Sequence

Gln18-Glu251(Leu136Gln)

Fusion Tag

C-Fc

Accession

P18827

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

51 kDa

AP Mol Mass

80-90 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Research Areas

Signal Transduction, Neuroscience, Cancer, metabolism, Stem cells

Reconstitution

Please refer to the printed manual for detailed information.

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