Fagus Antibody Services

Recombinant Human TMEM27 Protein (Fc Tag)

£585.60£732.00 excluding VAT

SKU FAS-030663-P Category Tag

TMEM27 is a membrane protein. It has been proposed as a beta cell mass biomarker since it is cleaved and shed by pancreatic beta cells. Overexpression of TMEM27 leads to increased thymidine incorporation, whereas silencing of Tmem27 using RNAi results in a reduction of cell replication. Furthermore, transgenic mice with increased expression of Tmem27 in pancreatic beta cells exhibit increased beta cell mass. TMEM27 is also important for trafficking amino acid transporters to the apical brush border of proximal tubules.

Size

100µg

Active Protein
Activity
Protein Construction

A DNA sequence encoding the human TMEM27 (Q9HBJ8) (Met1-Pro141) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Sequence

Met 1-Pro141

Fusion Tag

C-Fc

Accession

Q9HBJ8

Species

Human

Expressed Host

HEK293 Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

41.4 kDa

AP Mol Mass

53-57 kDa

Formulation

Lyophilized from sterile PBS, pH 7.4

Research Areas

Signal Transduction, metabolism

Reconstitution

Please refer to the printed manual for detailed information.

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