Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508).
In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Recombinant Human TNF β/LTA Protein
£128.00 – £360.00 excluding VAT
| Size | 20μg, 100μg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | A DNA sequence encoding the Human TNF β/LTA Protein(P01374)(Leu35-Leu205)was expressed with a polyhistidine tag at the N-terminus. |
| Sequence | Leu35-Leu205 |
| Fusion Tag | N-His |
| Accession | NP_000586.2 |
| Species | Human |
| Expressed Host | E.coli |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 18.7 kDa |
| AP Mol Mass | 19 kDa |
| Formulation | Lyophilized from sterile PBS, pH 7.4, 5% trehalose, 5% mannitol, 0.01% tween-80. |
| Research Areas | Cancer, Cardiovascular, Immunology, Cytokines |
| Reconstitution | Please refer to the printed manual for detailed information. |
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