Fagus Antibody Services

Recombinant Human TNFRSF1B/CD120b Protein (mFc Tag)

£103.20£375.00 excluding VAT

SKU FAS-033484-P Category

Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD; which shares 58% and 56% amino acid sequence identity with the mouse and rat orthologs; respectively.TNF RII is expressed predominantly on cells of the hematopoietic lineage; such as T and natural killer cells; as well as on endothelial cells; microglia; astrocytes;neurons; oligodendrocytes; cardiac myocytes; thymocytes; and mesenchymal stem cells.TNF RII binds to the membranebound forms of TNFα and Lymphotoxinα/TNFβ?soluble TNF is thought to signal predominately through TNF RI.Soluble TNF RII is believed to inhibit TNF biological activity by binding TNF thereby preventing it from activating membrane TNF receptors.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human TNFRSF1B is produced by our Mammalian expression system and the target gene encoding Pro24-Thr206 is expressed with a mFc tag at the C-terminus.

Sequence

Pro24-Thr206

Fusion Tag

C-mFc

Accession

P20333

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

46.44 kDa

AP Mol Mass

60 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Research Areas

Signal Transduction, Cell biology, Cardiovascular, Neuroscience, Cancer, immunology

Reconstitution

Please refer to the printed manual for detailed information.

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