Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is shown that UBE2B interacts with RAD18; UBR2; and WAC. UBE2B is required for post-replicative DNA damage repair. Additional; UBE2B plays a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
Recombinant Human UBE2B/HR6B Protein (His Tag)
£220.00 – £525.00 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Human Ubiquitin-Conjugating Enzyme E2 B is produced by our Mammalian expression system and the target gene encoding Met1-Ser152 is expressed with a 6His tag at the C-terminus. |
| Sequence | Met 1-Ser152 |
| Fusion Tag | C-6His |
| Accession | P63146 |
| Species | Human |
| Expressed Host | Human Cells |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per µg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 18.3 kDa |
| AP Mol Mass | 17 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.2. |
| Research Areas | Cell biology, Cancer, epigenetics and nuclear signal, metabolism |
| Reconstitution | Not Applicable |
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