Ubiquitin-conjugating enzyme E2 D1 (UBE2D1); a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is short for stimulator of iron (Fe) transport. In other words; UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis; as previously published for SFT. Moreover; a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.
Recombinant Human UBE2D1 Protein (His Tag)
£536.00 – £670.00 excluding VAT
| Size | 100µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed; with a polyhistide tag at the N-terminus. |
| Sequence | Ala 2-Met 147 |
| Fusion Tag | N-His |
| Accession | P51668 |
| Species | Human |
| Expressed Host | E.coli |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 18.3 kDa |
| AP Mol Mass | |
| Formulation | Lyophilized from sterile 25mM Tris, 100mM NaCl, 20% glycerol, 0.05% Tween |
| Research Areas | Cell biology, epigenetics and nuclear signal |
| Reconstitution | Please refer to the printed manual for detailed information. |
Related Product
Related products
-
-
-
Protein
Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD (C-mFc-6His tag)(Active)
£180.00 – £875.00 excluding VAT -
-
-
-
-
-
-