Fagus Antibody Services

Linkedin Twitter
Linkedin Twitter

Recombinant Human ULBP2/N2DL-2 Protein (Fc Tag)

£487.20 – £609.00 excluding VAT

SKU FAS-030893-P Category Tag

NKG2D ligand 2; also known as N2DL-2; NKG2DL2; ALCAN-alpha; Retinoic acid early transcript 1H; UL16-binding protein 2; ULBP2 and N2DL2; is cell membrane protein which belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus; but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor; together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells; resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2; STAT5; ERK and PI3K kinase/Akt signal transduction pathway.

Size

100µg
Active Protein
Activity
Protein Construction

A DNA sequence encoding the human ULBP2 (Q9BZM5) (Met 1-Ser 217);without the pro peptide; w was fused with the Fc region of human IgG1 at the C-terminus.
Sequence

Met 1-Ser 217
Fusion Tag

C-Fc
Accession

Q9BZM5
Species

Human
Expressed Host

HEK293 Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per µg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

48.7 kDa
AP Mol Mass

58 kDa
Formulation

Lyophilized from sterile PBS, pH 7.4
Research Areas

immunology
Reconstitution

Please refer to the printed manual for detailed information.

Related Product

Related products

All Products