Fagus Antibody Services

Recombinant Human VAPB Protein (His Tag)(Active)

£93.60£297.00 excluding VAT

vesicle-associated membrane protein-associated protein B/C (VAPB) is presents in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. It can form homodimer; and heterodimer with VAPA. It also interacts with VAMP1; VAMP2; HCV NS5A; NS5B; ZFYVE27 and RMDN3. VAPB participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. It is involved in cellular calcium homeostasis regulation.

Size

10µg, 50µg

Active Protein

Active protein

Activity

Immobilized Human EphB2-Fc(Cat: PKSH032012) at 1μg/ml(100 μl/well) can bind Human VAMPB-His. The ED50 of Human VAMPB-His is 5.179ug/ml .

Protein Construction

Recombinant Human Vesicle-associated membrane protein-associated protein B is produced by our E.coli expression system and the target gene encoding Ala2-Pro132 is expressed with a 6His tag at the C-terminus.

Sequence

Ala2-Pro132

Fusion Tag

C-6His

Accession

O95292-1

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

16.0 kDa

AP Mol Mass

16 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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