Fagus Antibody Services

Recombinant Macaca nemestrina PCSK9/Proprotein Convertase 9 Protein (His Tag)

£178.40£474.40 excluding VAT

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Macaca nemestrina PCSK9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln152&Ser153-Gln692 is expressed with a 6His tag at the C-terminus.

Sequence

Gln31-Gln152&Ser153-Gln692

Fusion Tag

C-His

Accession

A8T662

Species

Macaca nemestrina

Expressed Host

Human Cells

Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass

14&59 kDa

AP Mol Mass

18&70 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 20%Glycerol, pH 7.4.

Research Areas
Reconstitution

Not Applicable

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