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Recombinant Mouse 4-1BB/TNFRSF9 Protein (aa 24-187, Fc Tag)(Active)

£205.60 – £357.60 excluding VAT

SKU FAS-041199-P Category Tag

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

Size

10µg, 50µg
Active Protein

Active protein
Activity

Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.05μg/ml(100 μl/well) can bind Mouse 4-1BB-Fc.
Protein Construction

Recombinant Mouse 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Val24-Leu187 is expressed with a Fc tag at the C-terminus.
Sequence

Val24-Leu187
Fusion Tag

C-Fc
Accession

NP_001070976.1
Species

Mouse
Expressed Host

Human Cells
Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg as determined by the LAL method.
Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass

44.7 kDa
AP Mol Mass

60-70 kDa
Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Research Areas
Reconstitution

Not Applicable

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