CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Recombinant Mouse CD38 Protein (His Tag)
£178.40 – £474.40 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Mouse CD38 is produced by our Mammalian expression system and the target gene encoding Leu45-Thr304 is expressed with a 6His tag at the C-terminus. |
| Sequence | Leu45-Thr304 |
| Fusion Tag | C-His |
| Accession | P56528 |
| Species | Mouse |
| Expressed Host | Human Cells |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 30.6 kDa |
| AP Mol Mass | 38-47 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0. |
| Research Areas | |
| Reconstitution | Not Applicable |
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