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Recombinant Mouse CD6/TP120 Protein (His Tag)

£49.60 – £142.40 excluding VAT

SKU FAS-041351-P Category Tag

CD6 is a member of the group B scavenger receptor cysteinerich(SRCR) superfamily. CD6 is a type I membrane glycoprotein and contains three extracellularSRCR domains. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subsetof B cells, and a subset of neuronal cells express CD6. Mouse CD6 is a 626 amino acid (aa) protein with a 24 aa sequence, a 372 aa extracellular domain, and a204 aa cytoplasmic region. The role of CD6 has not been fully elucidated. However, it appears to play a role as both a costimulatorymolecule in T cell activation and as an adhesion receptor.CD6/ALCAM interactions have been postulated to play a role in thymocyte development. The CD6 intracellular domain contains regions that can interact with SH2 or SH3 containing proteins. However,the signaling pathways have not been elucidated.

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Mouse CD6 antigen is produced by our Mammalian expression system and the target gene encoding Leu18-Gly396 is expressed with a 6His tag at the C-terminus.
Sequence

Leu18-Gly396
Fusion Tag

C-His
Accession

Q91WN5
Species

Mouse
Expressed Host

Human Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 90 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

41.9 kDa
AP Mol Mass

60-90 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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