Fagus Antibody Services

Linkedin Twitter
Linkedin Twitter

Recombinant Mouse CD64/FCGR1 Protein (His Tag)

£73.60 – £171.20 excluding VAT

SKU FAS-041015-P Category Tag

CD64, also known as Fc-gamma receptor 1 (FcγRI), is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity. After binding IgG, CD64 interacts with an accessory chain known as the common γ chain (γ chain), which possesses an ITAM motif that is necessary for triggering cellular activation. CD64 is composed of a signal peptide, three extracellular immunoglobulin domains of the C2-type used to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. It is normally expressed on the surfaces of monocytes and macrophages.

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Mouse High affinity immunoglobulin gamma Fc receptor I is produced by our Mammalian expression system and the target gene encoding Glu25-Pro297 is expressed with a 6His tag at the C-terminus.
Sequence

Glu25-Pro297
Fusion Tag

C-6His
Accession

P26151
Species

Mouse
Expressed Host

Human Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

31.5 kDa
AP Mol Mass

40-60 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

Related Product

Related products

All Products