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Recombinant Mouse Fibrillin-1/FBN1 Protein (His Tag)

£142.40 – £418.40 excluding VAT

SKU FAS-041018-P Category Tag

Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Mouse Fibrillin-1 is produced by our Mammalian expression system and the target gene encoding Ser2732-His2871 is expressed with a 8His tag at the N-terminus.
Sequence

Ser2732-His2871
Fusion Tag

N-8His
Accession

Q61554
Species

Mouse
Expressed Host

Human Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 90 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

16.9 kDa
AP Mol Mass

30 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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