Fagus Antibody Services

Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)

£178.40£474.40 excluding VAT

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.

Sequence

Gly19-Ser247

Fusion Tag

C-6His

Accession

P04187

Species

Mouse

Expressed Host

Human Cells

Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity

> 85 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass

26.5 kDa

AP Mol Mass

35kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Research Areas
Reconstitution

Not Applicable

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