IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an essential component of intracellular signaling pathways that mobilize calcium. Mouse IMPAD1 exhibits 91% sequence identity with the human homologue.
Recombinant Mouse IMPAD1/IMP3 Protein (His Tag)
£205.60 – £357.60 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Mouse IMPAD1 is produced by our Mammalian expression system and the target gene encoding Glu51-His356 is expressed with a 6His tag at the N-terminus. |
| Sequence | Glu51-His356 |
| Fusion Tag | N-His |
| Accession | Q80V26 |
| Species | Mouse |
| Expressed Host | Human Cells |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 34.3 kDa |
| AP Mol Mass | 38 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 10%Glycerol, pH8.0. |
| Research Areas | |
| Reconstitution | Not Applicable |
