Fagus Antibody Services

Recombinant Mouse Interleukin-13/IL-13 Protein (aa 26-131,His Tag)(Active)

£142.40£418.40 excluding VAT

Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13Rα1 with low affinity and triggers association of IL4Rα, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13Rα2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.


10µg, 50µg

Active Protein

Active protein


Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 2-13 ng/ml.

Protein Construction

Recombinant Mouse Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Ser26-Phe131 is expressed with a 6His tag at the C-terminus.



Fusion Tag






Expressed Host

Human Cells


This product is provided as lyophilized powder which is shipped with ice packs.


> 95 % as determined by reducing SDS-PAGE.


< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

12.7 kDa

AP Mol Mass

15-30 kDa


Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Research Areas

Please refer to the printed manual for detailed information.

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