Fagus Antibody Services

Recombinant Mouse Interleukin-36 gamma/IL-36 gamma/IL-1F9

£296.00£886.40 excluding VAT

Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Mouse Interleukin-36 Gamma is produced by our E.coli expression system and the target gene encoding Gly13-Ser164 is expressed.

Sequence

Gly13-Ser164

Fusion Tag
Accession

Q8R460

Species

Mouse

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

17.3 kDa

AP Mol Mass

17 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 1 M MOPS, 10 mM NaAc, 2 mM EDTA, 5 % Trehalose, 0.02 % Tween-20, pH 7.6.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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