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Recombinant Mouse MGL2/CD301b Protein (His Tag)

£103.20 – £300.00 excluding VAT

SKU FAS-041306-P Category Tag

Macrophage galactose N-acetyl-galactosamine-specific lectin 2(Mgl2), also known as CD301b, is a 38 kDa member that belongs to the C-type lectin family. Two MGL proteins are encoded by separate genes in the mouse, but share 91% amino acid (aa) identity in the extracellular domain (ECD). Only one MGL occurs in human and rat and this MGL is structurally more similar to mouse MGL1 than MGL2. However, human MGL and mouse MGL2 both bind specifically to terminal GalNAc residues, in contrast with mouse MGL1 which binds Lewis X. GalNAc recognition is likely to be important in dendritic cell-mediated tolerance to self-gangliosides as well as recognition of tumor antigens and parasite glycoproteins.

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Mouse MGL2 is produced by our Mammalian expression system and the target gene encoding Ser72-Pro232 is expressed with a 6His tag at the N-terminus.
Sequence

Ser72-Pro232
Fusion Tag

N-His
Accession

Q8JZN1
Species

Mouse
Expressed Host

Human Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

30.9 kDa
AP Mol Mass

30-40 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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