Fagus Antibody Services

Recombinant Mouse Pentraxin-related protein PTX3(N-6His)

£251.20£736.80 excluding VAT

Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Mouse Pentraxin-related protein PTX3 is produced by our Mammalian expression system and the target gene encoding His18-Ser381 is expressed with a 6His tag at the N-terminus.

Sequence

His18-Ser381

Fusion Tag

N-6His

Accession

P48759

Species

Mouse

Expressed Host

Human Cells

Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass

41 kDa

AP Mol Mass

54 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Research Areas
Reconstitution

Not Applicable

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