Fagus Antibody Services

Recombinant Mouse RANKL/TNFSF11 Protein (Active)

£142.40£418.40 excluding VAT

SKU FAS-041166-P Category

Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Mouse TNF Ligand Superfamily Member 11 is produced by our E.coli expression system and the target gene encoding Lys158-Asp316 is expressed.

Sequence

Lys158-Asp316

Fusion Tag
Accession

O35235

Species

Mouse

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by SDS-PAGE

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

17.9 kDa

AP Mol Mass

18 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mMTris-HCl, 150mMNaCl, 1mMEDTA, pH8.0.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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