TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.
Recombinant Mouse TIM1/HAVCR1 Protein (His Tag)
£78.40 – £209.60 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Mouse TIM-1 is produced by our Mammalian expression system and the target gene encoding Tyr22-Thr212 is expressed with a 6His tag at the C-terminus. |
| Sequence | Tyr22-Thr212 |
| Fusion Tag | C-His |
| Accession | Q5QNS5 |
| Species | Mouse |
| Expressed Host | Human Cells |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 21.8 kDa |
| AP Mol Mass | 35-50 kDa |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Research Areas | |
| Reconstitution | Please refer to the printed manual for detailed information. |
