Fagus Antibody Services

Recombinant Mouse TPBG/5T4 (C-6His)

£157.60£471.20 excluding VAT

Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Mouse Trophoblast Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser361 is expressed with a 6His tag at the C-terminus.

Sequence

Ser32-Ser361

Fusion Tag

C-6His

Accession

Q9Z0L0

Species

Mouse

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

36.6 kDa

AP Mol Mass

50-70 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

Related Product