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Recombinant Rat Semaphorin 4D/SEMA4D/ Protein (His Tag)

£585.60 – £884.00 excluding VAT

SKU FAS-030236-P Category Tag

Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.

Size

100µg
Active Protein
Activity
Protein Construction

A DNA sequence encoding the rat SEMA4D (Met1-Met712) was expressed, fused with a polyhistidine tag at the C-terminus.
Sequence

Met1-Met712
Fusion Tag

C-His
Accession

NP_001164034.1
Species

Rat
Expressed Host

HEK293 Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

77.8 kDa
AP Mol Mass

96 kDa
Formulation

Lyophilized from sterile PBS, pH 7.4
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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