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Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-6His)

£74.40 – £221.60 excluding VAT

SKU FAS-050121-P Category Tag

Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

Size

10µg, 50µg
Active Protein

Active protein
Activity

Immobilized Rhesus Macaque TROP-2-His(Cat#PKSQ050121) at 2μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb .The ED50 of Anti-Human TROP-2 mAb is 4.7 ng/ml.
Protein Construction

Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2 is produced by our Mammalian expression system and the target gene encoding His27-Arg272 is expressed with a 6His tag at the C-terminus.
Sequence

His27-Arg272
Fusion Tag

C-6His
Accession

XP_001114599.1
Species

Rhesus macaque
Expressed Host

Human Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per µg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

28.7 kDa
AP Mol Mass

38-45 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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