TWISTNB (TWIST Neighbor) is a Protein Coding gene. Among its related pathways are Metabolism and RNA Polymerase I Promoter Escape. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters.