RUNX3 encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this Runt-related transcription factor 3 and a beta subunit forms a complex that binds to the core DNA sequence 5′-PYGPYGGT-3′ found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
RUNX3 Rabbit pAb
£118.40 – £248.00 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 864 |
| Applications | ELISA, WB |
| Reactivity | Human 1 |
| Host | Rabbit |
| Isotype | |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | |
| Clonality | Polyclonal |
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