This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
14-3-3 beta/alpha Polyclonal Antibody
£192.00 – £319.20 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P31946 |
| Applications | ELISA, IHC, WB |
| Reactivity | Human 1, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Cell Biology, Neuroscience, Signal Transduction, Stem Cells |
| Concentration | 0.4 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Synthetic peptide of human YWHAB |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Conjugation | Unconjugated |
| Clonality | Polyclonal |
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