This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5′ UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
14-3-3 theta Polyclonal Antibody
£192.00 – £319.20 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P27348 |
| Applications | ELISA, IHC, WB |
| Reactivity | Human 1, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells |
| Concentration | 0.5 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Synthetic peptide of human YWHAQ |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Dilution | WB 1:1000-1:5000, IHC 1:25-1:100 |
| Conjugation | Unconjugated |
| Clonality | Polyclonal |
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