Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
BCL2 Monoclonal Antibody
£192.00 – £319.20 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P10415 |
| Applications | IHC-p, WB |
| Reactivity | Human 1, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Synthetic Peptide |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Dilution | WB 1:1000-2000, IHC 1:50-1:200 |
| Conjugation | Unconjugated |
| Clonality | Monoclonal |
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