This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
C1GALT1C1 Polyclonal Antibody
£192.00 – £319.20 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | Q96EU7 |
| Applications | ELISA, IHC |
| Reactivity | Human 1, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Metabolism, Signal transduction |
| Concentration | 0.8 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Fusion protein of human C1GALT1C1 |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification Method | Antigen affinity purification |
| Dilution | IHC 1:50-1:300, ELISA 1:5000-1:10000 |
| Conjugation | Unconjugated |
| Clonality | Polyclonal |
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