SH3BP1 encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein’s association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues.
3BP1 Rabbit pAb
£118.40 – £319.20 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 23616 |
| Applications | ELISA, WB |
| Reactivity | Human 1, Mouse |
| Host | Rabbit |
| Isotype | |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | |
| Clonality | Polyclonal |
Related Product
Related products
-
-
-
-
Polyclonal Antibody
Cleaved-Plasminogen HC A short form (V98) Rabbit pAb
£76.00 – £248.00 excluding VAT -
-
-
-
-
-