Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3′ of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
COX4I1 Monoclonal Antibody
£192.00 – £319.20 excluding VAT
SKU
FAS-22002-A
Category Monoclonal Antibody
Tags AL024441, COX 4, COX IV, COX IV 1, COX IV-1, COX4, COX41, Cox4a, COX4B, COX4I1, COX4I2, COX4L2, COXIV, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, Cytochrome C Oxidase subunit IV, Cytochrome c oxidase subunit IV isoform 1, Cytochrome c oxidase subunit IV isoform 2 (lung), Cytochrome c oxydase subunit 4, dJ857M17.2, MGC105470, MGC72016, mitochondrial
Size | 120μL, 200μL |
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Swissprot | P13073 |
Applications | IF, IHC-p, WB |
Reactivity | Human 1, Mouse, Rat |
Host | Mouse |
Isotype | IgG |
Research Areas | Cancer, Metabolism, Signal Transduction, Tags and Cell Markers |
Concentration | 1 mg/mL |
Storage | Store at -20°C. Avoid freeze / thaw cycles. |
Immunogen | Recombinant Protein |
Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method | Protein A purification |
Dilution | WB 1:1000-3000, IHC 1:50-300, IF 1:100-1:300 |
Conjugation | Unconjugated |
Clonality | Monoclonal |
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