This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Desmin Polyclonal Antibody
£192.00 – £399.00 excluding VAT
SKU
FAS-31185-A
Category Polyclonal Antibody
Tags CMD1I, CSM1, CSM2, DES, DESM, Desmin, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865
Size | 120μL, 200μL |
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Swissprot | P17661 |
Applications | WB, IHC-p, IF, ELISA |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Research Areas | Cancer, Cardiovascular, Signal Transduction, Stem Cells |
Concentration | 1 mg/mL |
Storage | Store at -20°C. Avoid freeze / thaw cycles. |
Immunogen | Synthesized peptide derived from the C-terminal region of human Desmin |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000 |
Conjugation | Unconjugated |
Clonality | Polyclonal |
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