Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
FLK1 Polyclonal Antibody
£192.00 – £399.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P35968, P35918, O08775 |
| Applications | WB |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Cardiovascular, Metabolism, Microbiology, Signal Transduction, Stem Cells |
| Concentration | 1.1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse VEGFR2 |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Dilution | WB 1:500-1:1000 |
| Conjugation | Unconjugated |
| Clonality | Polyclonal |
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