This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.
Human, Mouse, Rat
Cancer, Immunology, Signal Transduction
Store at -20°C. Avoid freeze / thaw cycles.
Recombinant fusion protein of human CAPG (NP_001738.2).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
WB 1:500-1:2000 IHC 1:50-1:200
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