The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
(KO Validated) EGFR Polyclonal Antibody
£288.00 – £580.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P00533 |
| Applications | WB |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Signal Transduction |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | A synthetic peptide of human EGFR (NP_005219.2). |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Purification Method | Affinity purification |
| Dilution | WB 1:500-1:1000 |
| Conjugation | Unconjugated |
| Clonality | |
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