The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Human, Mouse, Rat
Cancer, Signal Transduction
Store at -20°C. Avoid freeze / thaw cycles.
A synthetic peptide of human EGFR (NP_005219.2).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
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